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The antitumorigenic activity of Plicamycin (0
In the presence of human colon cancer cells labeled with 3Hthymidine
ClH/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7
with the efficacy being markedly enhanced compared with the effects elicited by SMS 201-995 after 7 days of treatment
InChi: InChI=1S/C40H59NO11/c1-19-11-24-5-7-28-20(2)12-26(45-28)9-10-40-17-33-36(51-40)37-38(50-33)39(52-40)35-29(49-37)8-6-25(47-35)13-22(42)14-27-31(16-30(46-24)21(19)3)48-32(34(27)44-4)15-23(43)18-41/h19
PF-4693627 Size:Contact [email protected] for quotation The antitumorigenic activity of PlicamycinPF 4693627 is a potent, selective and orally bioavailable microsomal prostaglandin E synthase 1 (mPGES 1) inhibitor (IC50=3 nM) for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA). Product information CAS Number: 1312815 93 2 Molecular Weight: 502. 43 Formula: C26H29Cl2N3O3 Chemical Name: 1 [5 chloro 6 (4 chlorophenyl) 1,3 benzoxazol 2 yl] N [(1S,3S) 3 (hydroxymethyl)cyclohexyl]piperidine 4 carboxamide Smiles:
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