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Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM
Amifostine trihydrate is potent hypoxia-inducible factor-α1 (HIF-α1) and p53 inducer
InChiKey: IFCAWDLUIZXIPI-FJDAOBEISA-N
(S)-(-)-Bay-K-8644
InChiKey: UEJJHQNACJXSKW-SECBINFHSA-N
MK-0354 497 Sardomozide is an S-adenosylmethionine decarboxylaseMK 0354 is a partial agonist of GPR109a receptor, for hGPR109a mGPR109a with EC50 of 1. 65 1. 08 M, showed no activation of GPR109b. IC50 value: 1. 65 M (EC50, for hGPR109a), 1. 08 M (EC50, for mGPR109a) Target: GPR109ain vitro: MK 0354 demonstrated clear and statistically significant partial agonism in the cAMP assays for both the mouse and human receptors with efficacy approximately 60 70% of that of either nicotinic acid or hydroxy butyrate, a
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