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PubMed Central PMCID: PMC3562069
InChi: InChI=1S/C15H8F6N2O2/c16-14(17
InChiKey: ZGGHKIMDNBDHJB-VOEOVFABSA-M
CWHM12 not only worked the same way to prevent fibrosis as the genetic deletion method
HG-14-10-04 is a novel potent and specific ALK inhibitor
RGB-286638 free base anaxatriol PubMed Central PMCID: PMC3562069RGB 286638 is a multitargeted cyclin dependent kinase inhibitor. RGB 286638 triggers P53 dependent and independent anti multiple myeloma activity through inhibition of transcriptional CDKs. GB 286638 treatment resulted in MM cytotoxicity in vitro associated with inhibition of MM tumor growth and prolonged survival in vivo. RGB 286638 displayed caspase dependent apoptosis in both wt p53 and mutant p53 cells that was closely associated with the
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