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Antibody-drug conjugates (ADC) comprise targeting antibodies armed with potent small-molecule payloads
Smiles: CC1=C(C=CN=C1C[S@@](=O)C1NC2=CC=CC=C2N=1)OCC(F)(F)F
CAS Number: 901119-35-5
InChiKey: HTKFORQRBXIQHD-UHFFFAOYSA-N
SRI-011381 hydrochloride (10-75 mg/kg
AVL-292 Catalog No.:M11333-2 Antibody-drug conjugates (ADC) comprise targetingSpebrutinib, also known as AVL 292 or CC 292, is an orally bioavailable, selective inhibitor of Brutons agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Upon administration, AVL 292 targets and covalently binds to BTK, thereby preventing its activity. By irreversibly inhibiting BTK, administration of this agent may lead to an inhibition of B cell receptor (BCR) signaling and may inhibit cell proliferation of B cell
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