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RVX-208 - BET Bromodomain Inhibitor. CAS# 1044870-39-4 60428 Antje Dittmann

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Description

Antje Dittmann

(2009) Nat Biotechnol

Curr Pharm Des

RS-1: a RAD51-Stimulatory compound enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency

Hydroxychloroquine (HCQ) can be dosed to mice orally at 50 mg/Kg once per day

RVX-208 - BET Bromodomain Inhibitor. CAS# 1044870-39-4 60428 Antje DittmannRVX 208, CAS No. 1044870 39 4, also known as Apabetalone, is a potent inhibitor of BET bromodomains. RVX 208 functions by removing atherosclerotic plaque via reverse cholesterol transport (RCT). RVX 208 increases the production of ApoA I in hepatocytes in vitro, and in vivo in monkeys and humans, which results in increased HDL C, but the molecular target was not previously reported. RVX 208 may be a promising new approach to the treatment of

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