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Tariquidar 60314 Epub 2007 Sep 26

SKU: 60065018339

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Description

Epub 2007 Sep 26

3-diethyl-7-methyl-2

Chemical Name: 5-chloro-4-(1H-indol-3-yl)-N-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidin-2-amine

and guinea pig

AG1749 sodium

Tariquidar 60314 Epub 2007 Sep 26Tariquidar, also known as XR9576, is a P glycoprotein (P gp) inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non competitively binds to the p glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. Product information CAS

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