C-021 dihydrochloride dium formononetin-3'-sulfonate 48 h) inhibits the growth

48 h) inhibits the growth of human tumor cells with a GI50 of 10±6 µM

ALB-127158(a) produces a significant sustained decrease in body weight and food intake in the range of 5-15 mg/kg bid

EHop-016 also inhibits the Rac activity of MDA-MB-231 metastatic breast cancer cells and reduces Rac-directed lamellipodia formation in both cell lines

InChiKey: YWXYYJSYQOXTPL-SLPGGIOYSA-N

Chemical Name: N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide hydrochloride

C-021 dihydrochloride dium formononetin-3'-sulfonate 48 h) inhibits the growthC 021 dihydrochloride is a potent CC chemokine receptor 4 (CCR4) antagonist. C 021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C 021 effectively prevents human CCL22 derived [35S]GTPS from binding to the receptor with an IC50 of 18 nM. Product information CAS Number: 1784252 84 1 Molecular Weight: 540. 57 Formula: C27H43Cl2N5O2 Chemical Name: (4E) 2 {[1,4' bipiperidin] 1' yl}